Prednisone & Prednisolone
Dosage Forms Available:
- Transdermal Gel
- Oral Suspension
- Chew Treat
Prednisone and Prednisolone are glucocorticoid medications that are prescribed for many uses including reducing inflammation, suppressing the immune system, treating some types of cancer, and as a replacement when the body is not making enough glucocorticoid on its own. They can be beneficial in treating many diseases and disorders but should be given at the lowest effective dose for the shortest time period possible to reduce the chances of
How They Work
Prednisone and prednisolone are medications that mimic the activity of a naturally occurring hormone produced in the adrenal cortex called cortisol. Glucocorticoids act on almost every part of the body and have a wide range of effects including reducing inflammation, suppressing the immune system, inhibiting healing, altering mood, stimulating appetite, increasing the secretion of gastric acid, weakening muscles, thinning the skin, and more.
In your pet’s liver, prednisone is converted to prednisolone. Pets with severe liver problems are not able to make this conversion effectively, and many veterinarians believe that these pets should only be given prednisolone. Cats also have a limited ability to convert prednisone into prednisolone, so prednisolone is the preferred medication in this species.